Neil W. Woodward III is an American Naval officer and a former NASA astronaut.

Dominic Anthony "Tony" Antonelli is a retired NASA astronaut.

Eric Allen Boe is a United States Air Force fighter pilot Colonel, test pilot, a Civil Air Patrol member, and a NASA astronaut. He flew as the pilot of Space Shuttle missions STS-126 and STS-133.

Kevin Anthony Ford is a retired United States Air Force Colonel and a NASA astronaut. Ford has received a number of special honors and awards, some of which are the Air Force Meritorious Service Medal, Air Force Commendation Medal, Aerial Achievement Medal and the Armed Forces Expeditionary Medal. Ford has also logged more than 5,000 flying hours and also holds FAA commercial certificates for airplanes, helicopters and gliders. Ford has served in many roles at NASA since his selection in July 2000. The roles include as a Capsule Communicator or CAPCOM. He was also the Director Of Operations at the Gagarin Cosmonaut Training Center in Star City, Russia from January 2004 to January 2005. He was pilot of STS-128 and Flight Engineer 2 of Soyuz TMA-06M from October 23, 2012 to March 16, 2013.

Ronald John Garan Jr. is a NASA astronaut. After graduating from State University of New York College at Oneonta in 1982, he joined the Air Force, becoming a Second Lieutenant in 1984. He became an F-16 pilot, and flew combat missions in Desert Shield and Desert Storm. Before becoming an astronaut he was the Operations Officer of the 40th Flight Test Squadron (FTS). He first flew in space as a Mission Specialist on the STS-124 mission to the International Space Station (ISS). He returned to ISS on April 4, 2011, for a six-month stay as a member of Expedition 27.

Barry Eugene "Butch" Wilmore is a NASA astronaut and United States Navy test pilot. He has had two spaceflights, the first of which was an 11-day Space Shuttle mission in November 2009, to the International Space Station. Wilmore was designated as pilot with five other crew members on Space Shuttle Atlantis for the mission STS-129. He most recently served as part of Expedition 41 to the International Space Station. Prior to being selected as a NASA astronaut in July 2000, Wilmore was an experienced Navy test pilot. He also participated in the development of T-45 Goshawk trainer jet.

Michael Reed Barratt is an American physician and a NASA astronaut. Specializing in aerospace medicine, he served as a flight surgeon for NASA before his selection as an astronaut, and has played a role in developing NASA's space medicine programs for both the Shuttle-Mir Program and International Space Station. His first spaceflight was a long-duration mission to the International Space Station, as a Flight Engineer in the Expedition 19 and 20 crew. In March 2011, Barratt completed his second spaceflight as a crew member of STS-133.

Robert Louis "Bob" Behnken is a United States Air Force officer, retired NASA astronaut and former Chief of the Astronaut Office. Behnken holds a Ph.D in Mechanical Engineering and holds the rank of Colonel in the U.S. Air Force. Col. Behnken has logged over 1,000 flight hours in 25 different aircraft. He flew aboard Space Shuttle missions STS-123 and STS-130 as a Mission Specialist, accumulating over 378 hours in space, including 19 hours of spacewalk time. Behnken was also assigned as Mission Specialist 1 to the STS-400 rescue mission. He is married to fellow astronaut K. Megan McArthur.

Stephen Gerard Bowen is a United States Navy submariner and a NASA astronaut; he was the second submariner to travel into space. Bowen has been on three spaceflights, all of which were Space Shuttle missions to the International Space Station. His first mission, STS-126, took place in November 2008, and his second was STS-132 in May 2010. In March 2011, Bowen completed his third spaceflight as a Mission Specialist on STS-133, which was Space Shuttle Discovery's final planned flight. Having flown on both STS-132 and STS-133, Bowen became the first and only astronaut to fly on consecutive shuttle missions. Originally Tim Kopra was scheduled to fly on STS-133, but Kopra had a bicycle injury shortly before the mission, and so he was replaced by Bowen.

Colonel Benjamin Alvin Drew is a United States Air Force officer and a NASA astronaut. He has been on two spaceflights; the first was the Space Shuttle mission STS-118 to the International Space Station, in August 2007. Drew's second spaceflight took place in March 2011 on STS-133, another mission to the International Space Station. STS-133 was Space Shuttle Discovery's final mission. Drew took part in two spacewalks while docked to the station. Drew was the final African-American to fly on board a Space Shuttle, as the final two Space Shuttle missions, STS-134 and STS-135, had no African-American crew members. He also is currently the latest African-American Astronaut to fly in space. Drew was selected to be an astronaut in NASA's Astronaut Group 18 in July 2000. Following his rookie spaceflight, Drew spent almost a year at the Yuri Gagarin Cosmonauts Training Center in Star City, Russia, overseeing NASA's training operations there as Director of Operations. On February 28, 2011, Drew became the 200th person to walk in space, when he conducted the first spacewalk of the STS-133 mission with fellow astronaut Steve Bowen.

Michael Timothy "Bueno" Good is a NASA astronaut and retired commissioned officer in the United States Air Force, holding the rank of Colonel. Mike Good flew aboard Space Shuttle Atlantis for its STS-125 mission. STS-125 was the final Hubble Space Telescope servicing mission. Good flew as Mission Specialist 2 on STS-132.

Timothy Lennart "Tim" Kopra is an engineer, a Colonel in the United States Army and a retired NASA astronaut. He served aboard the International Space Station as a flight engineer for Expedition 20, returning to Earth aboard Space Shuttle Discovery on the STS-128 mission on September 11, 2009. He returned to the ISS for the second time in December 2015, as part of Expedition 46 and as the Commander of 47.